Essential Guide to Reading Biomedical Papers: Recognising and Interpreting Best Practice is an indispensable companion to the biomedical literature. This concise, easy-to-follow text gives an insight into core techniques and practices in biomedical research and how, when and why a technique should be used and presented in the literature. Readers are alerted to common failures and misinterpretations that may evade peer review and are equipped with the judgment necessary to be properly critical of the findings claimed by research articles. This unique book will be an invaluable resource for students, technicians and researchers in all areas of biomedicine. Allows the reader to develop the necessary skills to properly evaluate research articles Coverage of over 30 commonly-used techniques in the biomedical sciences Global approach and application, with contributions from leading experts in diverse fields
A fundamental and straightforward guide to using and understanding statistical concepts in medical research Designed specifically for healthcare practitioners who need to understand basic biostatistics but do not have much time to spare, The Essentials of Biostatistics for Physicians, Nurses and Clinicians presents important statistical methods used in today's biomedical research and provides insight on their appropriate application. Rather than provide detailed mathematics for each of these methods, the book emphasizes what healthcare practitioners need to know to interpret and incorporate the latest biomedical research into their practices. The author draws from his own experience developing and teaching biostatistics courses for physicians and nurses, offering a presentation that is non-technical and accessible. The book begins with a basic introduction to the relationship between biostatistics and medical research, asking the question «why study statistics?,» while also exploring the significance of statisitcal methods in medical literature and clinical trials research. Subsequent chapters explore key topics, including: Correlation, regression, and logistic regression Diagnostics Estimating means and proportions Normal distribution and the central limit theorem Sampling from populations Contingency tables Meta-analysis Nonparametric methods Survival analysis Throughout the book, statistical methods that are often utilized in biomedical research are outlined, including repeated measures analysis of variance, hazard ratios, contingency tables, log rank tests, bioequivalence, cross-over designs, selection bias, and group sequential methods. Exercise sets at the end of each chapter allow readers to test their comprehension of the presented concepts and techniques. The Essentials of Biostatistics for Physicians, Nurses, and Clinicians is an excellent reference for doctors, nurses, and other practicing clinicians in the fields of medicine, public health, pharmacy, and the life sciences who need to understand and apply statistical methods in their everyday work. It also serves as a suitable supplement for courses on biostatistics at the upper-undergraduate and graduate levels.
A comprehensive reference of cutting-edge advanced techniques for quantitative image processing and analysis Medical diagnostics and intervention, and biomedical research rely progressively on imaging techniques, namely, the ability to capture, store, analyze, and display images at the organ, tissue, cellular, and molecular level. These tasks are supported by increasingly powerful computer methods to process and analyze images. This text serves as an authoritative resource and self-study guide explaining sophisticated techniques of quantitative image analysis, with a focus on biomedical applications. It offers both theory and practical examples for immediate application of the topics as well as for in-depth study. Advanced Biomedical Image Analysis presents methods in the four major areas of image processing: image enhancement and restoration, image segmentation, image quantification and classification, and image visualization. In each instance, the theory, mathematical foundation, and basic description of an image processing operator is provided, as well as a discussion of performance features, advantages, and limitations. Key algorithms are provided in pseudo-code to help with implementation, and biomedical examples are included in each chapter. Image registration, storage, transport, and compression are also covered, and there is a review of image analysis and visualization software. The accompanying live DVD contains a selection of image analysis software, and it provides most of the algorithms from the book so readers can immediately put their new knowledge to use. Members of the academic community involved in image-related research as well as members of the professional R&D sector will rely on this volume. It is also well suited as a textbook for graduate-level image processing classes in the computer science and engineering fields.
An essential guide to healthcare data problems, sources, and solutions Strategies in Biomedical Data Science provides medical professionals with much-needed guidance toward managing the increasing deluge of healthcare data. Beginning with a look at our current top-down methodologies, this book demonstrates the ways in which both technological development and more effective use of current resources can better serve both patient and payer. The discussion explores the aggregation of disparate data sources, current analytics and toolsets, the growing necessity of smart bioinformatics, and more as data science and biomedical science grow increasingly intertwined. You'll dig into the unknown challenges that come along with every advance, and explore the ways in which healthcare data management and technology will inform medicine, politics, and research in the not-so-distant future. Real-world use cases and clear examples are featured throughout, and coverage of data sources, problems, and potential mitigations provides necessary insight for forward-looking healthcare professionals. Big Data has been a topic of discussion for some time, with much attention focused on problems and management issues surrounding truly staggering amounts of data. This book offers a lifeline through the tsunami of healthcare data, to help the medical community turn their data management problem into a solution. Consider the data challenges personalized medicine entails Explore the available advanced analytic resources and tools Learn how bioinformatics as a service is quickly becoming reality Examine the future of IOT and the deluge of personal device data The sheer amount of healthcare data being generated will only increase as both biomedical research and clinical practice trend toward individualized, patient-specific care. Strategies in Biomedical Data Science provides expert insight into the kind of robust data management that is becoming increasingly critical as healthcare evolves.
Research Writing in Dentistry provides you with a uniquely practical guide to selecting, designing, and writing up a research project. Of particular use to the dental student, both pre- and post-doctoral, this is a no-nonsense guide that presents concrete advice and information that can be absorbed quickly and effectively. By asking simple questions, this useful resource enables you to develop, analyze and present a program of research work. It begins with the basic principles of research: what it is and how to select a topic and plan a program. It then moves on to discuss study design, methods and materials, presenting results and undertaking a literature review. It concludes with a section on basic statistics and analysis. Precepts and guidance are illustrated throughout with examples from dentistry.
Quickly acquire the knowledge and skills you need to confidently administer, score, and interpret a variety of storytelling techniques Storytelling techniques are a popular projective approach for assessing many aspects of a person's personality, such as cognitive processes, emotional functioning, and self-regulation. The broad spectrum of techniques includes the Thematic Apperception Test (TAT—the most widely embraced), Roberts-2, and TEMAS (Tell-Me-A-Story). To use these tests properly, professionals need an authoritative source of advice and guidance on how to administer, score, and interpret them. Written by Hedwig Teglasi, a leading researcher of the TAT and other storytelling techniques, Essentials of TAT and Other Storytelling Assessments, Second Edition is that source. Like all the volumes in the Essentials of Psychological Assessment series, this book is designed to help busy mental health professionals, and those in training, quickly acquire the knowledge and skills they need to make optimal use of major psychological assessment instruments. Each concise chapter features numerous callout boxes highlighting key concepts, bulleted points, and extensive illustrative material, as well as test questions that help you gauge and reinforce your grasp of the information covered. Fully revised and updated to reflect the current research supporting storytelling techniques, Essentials of TAT and Other Storytelling Assessments, Second Edition reflects the latest data and theory on scoring stories and includes new material on interpreting stories in reference to a person's abilities in cognition, emotion, relationships, motivation, and self-regulation. As well, the author provides expert assessment of the methods' relative strengths and weaknesses, valuable advice on their clinical applications, and several case studies to illustrate best practices for implementing the storytelling approach to personality assessment. Other titles in the Essentials of Psychological Assessment series: Essentials of Assessment Report Writing Essentials of PAI Assessment Essentials of 16PF Assessment Essentials of Neuropsychological Assessment, Second Edition Essentials of MillonTM Inventories Assessment, Third Edition Essentials of Rorschach Assessment Essentials of MMPI-2 Assessment Essentials of MMPI-A Assessment
This concise paperback is one of the best known guides to writing a paper for publication in biomedical journals. Its straightforward format – a chapter covering each of part of the structured abstract – makes it relevant and easy to use for any novice paper writer. How to Write a Paper addresses the mechanics of submission, including electronic submission, and how publishers handle papers, writing letters to journals abstracts for scientific meetings, and assessing papers. This new edition also covers how to write a book review and updated chapters on ethics, electronic publication and submission, and the movement for open access.
Surgical Essentials of Immediate Implant Dentistry provides a definitive text on this important treatment modality. Assisting readers to make sense of the various clinical techniques and protocols, Beagle discusses the available underlying evidence to provide a practical, comprehensive and navigable aid to attaining a thorough understanding of this complex and highly relevant subject. All aspects of immediate placement of endosseous implants are clearly and scientifically discussed, enabling the reader to survey the entire subject area, fusing clinical guidance with scientific discussion. Surgical Essentials of Immediate Implant Dentistry takes pre-operative risk assessment and indications and contraindications for immediate loading as its logical starting point. It then proceeds to examine the treatment of infected sites, extraction site healing, methods of extraction, surgical protocol, and finishes with a discussion of complications. Surgical Essentials of Immediate Implant Dentistry will find a ready place within libraries of oral and maxillofacial surgeons, periodontists and prosthodontists and will provide all dentists with an interest in implant dentistry with a useful and welcome companion to this expanding area of clinical practice and research.
This book grew out of an online interactive offered through statcourse.com, and it soon became apparent to the author that the course was too limited in terms of time and length in light of the broad backgrounds of the enrolled students. The statisticians who took the course needed to be brought up to speed both on the biological context as well as on the specialized statistical methods needed to handle large arrays. Biologists and physicians, even though fully knowledgeable concerning the procedures used to generate microaarrays, EEGs, or MRIs, needed a full introduction to the resampling methods—the bootstrap, decision trees, and permutation tests, before the specialized methods applicable to large arrays could be introduced. As the intended audience for this book consists both of statisticians and of medical and biological research workers as well as all those research workers who make use of satellite imagery including agronomists and meteorologists, the book provides a step-by-step approach to not only the specialized methods needed to analyze the data from microarrays and images, but also to the resampling methods, step-down multi-comparison procedures, multivariate analysis, as well as data collection and pre-processing. While many alternate techniques for analysis have been introduced in the past decade, the author has selected only those techniques for which software is available along with a list of the available links from which the software may be purchased or downloaded without charge. Topical coverage includes: very large arrays; permutation tests; applying permutation tests; gathering and preparing data for analysis; multiple tests; bootstrap; applying the bootstrap; classification methods; decision trees; and applying decision trees.
A must-have compendium on biomedical telemetry for all biomedical professional engineers, researchers, and graduate students in the field Handbook of Biomedical Telemetry describes the main components of a typical biomedical telemetry system, as well as its technical challenges. Written by a diverse group of experts in the field, it is filled with overviews, highly-detailed scientific analyses, and example applications of biomedical telemetry. The book also addresses technologies for biomedical sensing and design of biomedical telemetry devices with special emphasis on powering/integration issues and materials for biomedical telemetry applications. Handbook of Biomedical Telemetry: Describes the main components of a typical biomedical telemetry system, along with the technical challenges Discusses issues of spectrum regulations, standards, and interoperability—while major technical challenges related to advanced materials, miniaturization, and biocompatibility issues are also included Covers body area electromagnetics, inductive coupling, antennas for biomedical telemetry, intra-body communications, non-RF communication links for biomedical telemetry (optical biotelemetry), as well as safety issues, human phantoms, and exposure assessment to high-frequency biotelemetry fields Presents biosensor network topologies and standards; context-aware sensing and multi-sensor fusion; security and privacy issues in biomedical telemetry; and the connection between biomedical telemetry and telemedicine Introduces clinical applications of Body Sensor Networks (BSNs) in addition to selected examples of wearable, implantable, ingestible devices, stimulator and integrated mobile healthcare system paradigms for monitoring and therapeutic intervention Covering biomedical telemetry devices, biosensor network topologies and standards, clinical applications, wearable and implantable devices, and the effects on the mobile healthcare system, this compendium is a must-have for professional engineers, researchers, and graduate students.
Step-by-step guidance and the latest research findings on the basics of processing assessment Now in its Second Edition, Essentials of Processing Assessment provides critical information about this important aspect of cognitive functioning. This practical resource provides students and practitioners with the tools they need to accurately and efficiently assess an individual's ability to process information. As part of the Essentials of Psychological Assessment series, this book provides information mental health professionals need to practice knowledgeably, efficiently, and ethically in today's behavioral healthcare environment. Includes illustrative material, callout boxes highlighting key concepts, and «test yourself» question for gauging and reinforcing learning Update throughout to include four new chapters and a new companion CD-ROM that includes all worksheets and testing charts Packed with indispensable guidelines on organizing a processing assessment and interpreting results Essentials of Processing Assessment, Second Edition, offers the best one-stop source of information to help students and practitioners identify processing strengths and weaknesses and plan appropriate interventions.
Explores bioconjugate properties and applications of polymers, dendrimers, lipids, nanoparticles, and nanotubes Bioconjugation has enabled breakthroughs across many areas of industry and biomedicine. With its emphasis on synthesis, properties and applications, this book enables readers to understand the connection between chemistry and the biological application of bioconjugated materials. Its detailed descriptions of methods make it possible for researchers to fabricate and take full advantage of bioconjugates for a broad range of applications. Moreover, the book sets the foundation for the development of new applications, including assays, imaging, biosensors, drug delivery, and diagnostics. Chemistry of Bioconjugates features contributions from an international team of leading experts and pioneers in the field. These contributions reflect the authors’ firsthand laboratory experience as well as a thorough review of the current literature. The book’s six sections examine: General methods of bioconjugation Polymer bioconjugates Organic nanoparticle-based bioconjugates Inorganic nanomaterial bioconjugates, including metals and metal oxides Cell-based, hydrogel/microgel, and glyco-bioconjugates Characterization, physico-(bio)chemical properties, and applications of bioconjugates This comprehensive exploration of bioconjugates includes discussions of polymers, dendrimers, lipids, nanoparticles, and nanotubes. References at the end of each chapter serve as a gateway to the most important original research findings and reviews in the field. By drawing together and analyzing all the latest chemical methods and research findings on the physico-chemical and biochemical properties of bioconjugates, Chemistry of Bioconjugates sheds new light on the significance and potential of bioconjugation. The book is recommended for organic and polymer chemists, biochemists, biomaterial scientists, carbohydrate chemists, biophysicists, bioengineers, and drug and gene delivery scientists.
A practical, insightful guide to the moral and ethical standards of healthcare Succeeding in the healthcare field means more than just making a diagnosis and writing a prescription. Healthcare professionals are responsible for convincing patients and their family members of the best course of action and treatments to follow, while knowing how to make the right moral and ethical choices, and so much more. Unlike daunting and expensive texts, Medical Ethics For Dummies offers an accessible and affordable course supplement for anyone studying medical or biomedical ethics. • Follows typical medical and biomedical ethics courses • Covers real ethical dilemmas doctors, nurses and other healthcare workers may face • Includes moral issues surrounding stem cell research, genetic engineering, euthanasia, and more Packed with helpful information, Medical Ethics For Dummies arms aspiring medical professionals with the philosophical and practical foundation for advancing in a field where critical ethical and moral decisions need to be rapidly and convincingly made.
Tribology is the “science and technology of interacting surfaces in relative motion” and encompasses the study of friction, wear and lubrication. By extension biotribology is usually defined as the tribological phenomena occurring in either the human body or in animals. Therefore, it is possible to consider tribological processes that may occur after implantation of an artificial device in the human body and the tribological processes naturally occurring in or on the tissues and organ of animals. Animals, including humans, possess a wide variety of sliding and frictional interfaces. The authors aim to provide some advances in research in biotribology. They cover several aspects of biotribology such as tribology of synovial joints and artificial replacements; wear of screws and plates in bone fractures repair; wear of denture and restorative materials; friction of the skin and comfort of clothing; wear of replacement heart valves; tribology of contact lenses and ocular tribology; biotribology on the microscale and nanoscale levels, etc. This book can be used as a research text for final undergraduate engineering courses (for example, materials, biomedical, etc.) or for those studying the subject of biotribology at the postgraduate level. It can also serve as a useful reference for academics, biomechanical researchers, biologists, chemists, physicists, biomedicals and materials engineers, and other professionals in related engineering, medicine and biomedical industries.
This is a compact but comprehensive guide to writing clearly and effectively in APA style. Demonstrates how to write objective scientific research papers using interesting prose Incorporates guidelines from the 6th edition of the APA publication manual Explores how to develop ideas, connect them to what others have written, and express them clearly Discusses the differences between written, oral, and poster presentations and offers instructions for applying APA style to each
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Полный, неадаптированный текст произведения.
The Pickwick Papers is Dickens first novel and widely regarded as one of the major classics of comic writing in English. Originally serialised in monthly instalments, it quickly became a huge popular success with sales reaching 40,000 by the final number. In the century and a half since its first appearance, the characters of Mr Pickwick, Sam Weller and the whole of the Pickwickian crew have entered the consciousness of all who love English literature in general, and the works of Dickens in particular.
Producing a dissertation has become a major requirement of most university courses, both undergraduate and Masters. It's likely to be the largest single piece of work you'll have to submit – and also the hardest! Writing a Dissertation For Dummies walks you through all the practical and theoretical aspects of writing a dissertation to help you produce a first-class work. This guide is ideal for any student in the broad range of the social sciences, from anthropology to law, psychology to media studies. From choosing a topic, to researching the literature, utilising your supervisor, managing your time, and structuring and writing your dissertation, you'll be able to avoid all the common mistakes and stay on top of your workload throughout the process. You'll also find tips on the best way to reference your work, and expert advice on presentation and binding. This is a must if you want to maximise your marks on your university dissertation. Writing a Dissertation For Dummies covers: Part I: What is a Dissertation? Chapter 1: So You Have to Write a Dissertation Chapter 2: Thinking About a Research Question Part II: Getting Set Up for Your Dissertation Chapter 3: The Structure of Your Dissertation Chapter 4: Getting Started Chapter 5: Finalising Your Research Question, Dissertation 'Type' And Considering Ethics Chapter 6: Reading Efficiently and Taking Useful Notes Part III: Getting On With Your Research Chapter 7: Researching in Libraries and the Using the Internet Chapter 8: Creating Your Own Empirical Data Chapter 9: Analysing Data And Drawing Conclusions Chapter 10: Staying on Track Part IV: Writing and Polishing Chapter 11: Managing Your Argument: 'Writing Up' Your Non-Empirical Dissertation Chapter 12: Writing Up Your Empirical Dissertation Chapter 13: Writing Effectively Chapter 14: References, Bibliographies and Appendices Chapter 15: Sorting Out The Presentation of Your Dissertation Part V: Managing The Overall Experience Chapter 16: Your Work Habits Chapter 17: Looking After Yourself Physically and Emotionally Chapter 18: Ten Common Dissertation Pitfalls to Avoid Chapter 19: Ten Essential Tips For Completing Your Dissertation Chapter 20: Ten Items For Your Very Final Checklist
Written by a leading expert on Aspirin-related research, this is the first comprehensive treaty of the history, pharmacological effects and clinical applications of one of the most successful drugs ever. The text is written with a wide audience in mind and to be readily understandable for clinicians as well as biomedical researchers and pharmacologists alike. The content is up to date and includes the latest results of clinical and academic research, with a balanced view on the disputed properties of this famous drug.
The essential guide to creating an organization ofhigh integrity and superior performance With the high-profile corporate scandals that have taken place in recent years, corporate ethics are more important to a business than ever before. The failure of ethical leadership in an organization is very destructive-it demoralizes the workforce, breeds public distrust, and ultimately results in organizational decay. Based on more than two decades of consulting, teaching, and research, Denis Collins's Essentials of Business Ethics is designed with appreciation for your demanding professional obligations, with easy-to-find, at-your-fingertips information. Its nuts-and-bolts presentation provides you with practical «how-to» examples and best practices on every area of managing ethics inside your organization in a handy, concise format. This brief yet powerful guide presents executives and leaders with timely discussion on: Human nature and unethical behavior in organizations Determining the ethics of job candidates The differences between a Code of Ethics and a Code of Conduct The best practices for managing diversity Using Management-by-Objectives to establish work goals that encourage ethical behavior Performance appraisals that reward ethical behaviors Aligning community outreach with the company's mission and assets Handling the environmental change process How to manage three internal communication mechanisms for employees to report potentially unethical or illegal behaviors: an Ethics & Compliance Office, Ombudsman, and Ethics Hotlines Providing a five-step ethics job-screen process and an ethical decision-making framework, as well as guidelines for conducting a variety of business ethics workshops, Essentials of Business Ethics is the only guide you will need containing all the relevant facts on business ethics, all in one place.
Quickly acquire the knowledge and skills you need to confidently administer, score, and interpret the key assessment instruments used by forensic psychologists Mental health professionals are frequently called on to perform forensic assessments for a wide variety of court cases. To use these instruments properly, professionals need an authoritative source of advice and guidance on how to administer, score, and interpret them. Now fully revised and in a second edition, Essentials of Forensic Psychological Assessment is that source. The Second Edition is completely updated to reflect current research and theory in the field, including the most recent codes and standards published by the American Psychological Association. In addition, this volume offers updated coverage of the most frequently used instruments in forensic psychological assessments, including the MMPI®-2 and MMPI-2-RF, PAI®, Rorschach®, ASPECT, and various neuropsychological assessment instruments. Like all the volumes in the Essentials of Psychological Assessment series, this book is designed to help busy mental health practitioners, and those in training, quickly acquire the knowledge and skills they need to make optimal use of major psychological assessment instruments. Each concise chapter features numerous callout boxes highlighting key concepts, bulleted points, and extensive illustrative material, as well as test questions that help you gauge and reinforce your grasp of the information covered. Written by a noted forensic psychologist, the Second Edition offers in-depth coverage of maltreatment and domestic violence, as well as the assessment of recidivism, fitness to stand trial, civil commitment, substance abuse assessment, custody evaluations, personal injury assessments, and many other aspects of forensic mental health practice.
Opinion leaders in science and politics examine findings and legislation in alternatives to animal testing! Refine, reduce, replace – These are the three demands that scientists have placed upon themselves in their search for alternatives to animal testing. Indeed much interdisciplinary research is being carried on today, and new fields have emerged, such as in-vitro toxicology. The three R's call for new scientific insights. Moreover, validation and acceptance strategies have to be adapted, a process of much ongoing interest and vital concern to the pharmaceutical and cosmetic industries. Researchers need to know exactly what has been achieved and accepted in alternatives to animal testing in science and politics. In this book they have the opportunity to benefit from the knowledge and expertise of leading researchers and influential representatives of national and international regulatory authorities.
The fun and easy way to learn essential grammar rules, common usage errors, and other key concepts in the English language Understanding the rules of English is key to being an effective communicator—at work, at school, or anywhere else. If you struggle with the rules—and who hasn't?—English Grammar Essentials For Dummies, Australian Edition is the book for you. Covering just the basics you need, the book boils the rules of grammar down to the core concepts that will make you a better communicator in any and every aspect of your life. Ideal for students, job hunters, adult learners, those who speak English as a second language, and anyone who wants to make a good impression Covers the vital essentials needed for better written communication Serves as an excellent refresher course for professionals whose primary mode of communication is increasingly electronic and written Clear and understandable writing can be the key to success in almost any professional field. With English Grammar Essentials For Dummies, Australian Edition, you'll master the basics with ease!
Published by the American Geophysical Union as part of the Special Publications Series. Opening Space Research: Dreams, Technology, and Scientific Discovery is George Ludwig's account of the early development of space-based electromagnetic physics, with a focus on the first U.S. space launches and the discovery of the Van Allen radiation belts. Narrated by the person who developed many of the instruments for the early Explorer spacecraft during the 1950s and participated directly in the scientific research, it draws heavily upon the author's voluminous collection of laboratory notes and other papers, upon the Van Allen archive, and upon a wide array of other sources. This book presents very detailed discussions of historic events in a highly readable (semitechnical), first-person form. More than that, though, Opening Space Research brings to the forefront the entire team of scientists who made these accomplishments possible, providing an extensive index of names to enhance and complete the historical record. Authoritative and unique, this book will be of interest to space scientists, science historians, and anyone interested in space history and the first U.S. space launches.
A fast and easy way to write winning white papers! Whether you’re a marketing manager seeking to use white papers to promote your business, or a copywriter keen to break into this well-paying field, White Papers For Dummies gives you a wealth of practical, hands-on advice from one of the world’s leading experts in the field. The fact-based documents known as white papers have been called the “king of content.” No other B2B marketing piece can do more to generate leads, nurture prospects, and build mindshare. Where white papers were once used only by technology firms, they are becoming “must-have” items in the marketing toolkit for almost any B2B firm. Practically every startup must produce a white paper as part of its business planning. But writing effective white papers is a big challenge. Now you can benefit from the experience of a white paper specialist who’s done more than 200 projects for clients from Silicon Valley to Finland, from mighty Google to tiny startups. Author Gordon Graham—also known as That White Paper Guy—provides dozens of tips and tricks to help your project come together faster and easier. White Papers For Dummies will help you to: Quickly determine if your B2B firm could benefit from a white paper Master the three phases of every white paper project: planning, production, and promotion Understand when and how to use the three main types of white paper Decide which elements to include and which to leave out Learn the best practices of seasoned white paper researchers and writers Choose from 40 different promotional tactics to get the word out Avoid common mistakes that many beginners make
An original account of willful ignorance and how this principle relates to modern probability and statistical methods Through a series of colorful stories about great thinkers and the problems they chose to solve, the author traces the historical evolution of probability and explains how statistical methods have helped to propel scientific research. However, the past success of statistics has depended on vast, deliberate simplifications amounting to willful ignorance, and this very success now threatens future advances in medicine, the social sciences, and other fields. Limitations of existing methods result in frequent reversals of scientific findings and recommendations, to the consternation of both scientists and the lay public. Willful Ignorance: The Mismeasure of Uncertainty exposes the fallacy of regarding probability as the full measure of our uncertainty. The book explains how statistical methodology, though enormously productive and influential over the past century, is approaching a crisis. The deep and troubling divide between qualitative and quantitative modes of research, and between research and practice, are reflections of this underlying problem. The author outlines a path toward the re-engineering of data analysis to help close these gaps and accelerate scientific discovery. Willful Ignorance: The Mismeasure of Uncertainty presents essential information and novel ideas that should be of interest to anyone concerned about the future of scientific research. The book is especially pertinent for professionals in statistics and related fields, including practicing and research clinicians, biomedical and social science researchers, business leaders, and policy-makers.
Medical students and junior and senior doctors are frequently called upon to give research presentations, write reports, and answer exam questions on specific areas of medical research. Understanding Medical Research: The Studies That Shaped Medicine is an exciting new title that offers a unique and valuable approach to understanding historically influential studies in important areas of medicine. Featuring chapters from Sir Liam Donaldson and Sir David Weatherall, amongst others, world leading researchers identify ten primary research papers that have shaped the direction of research in their given topic, examining why they were carried out, key findings, and how they changed the field. Each chapter also contains short sections on ‘Key Questions Remaining’ which outline outstanding areas where further research is needed, and a link to ‘Key Laboratories/Clinics’ which point the reader to major research groups of international standing. Covering the seminal research in core areas of medicine, Understanding Medical Research provides an authoritative framework on each topic for medical students and healthcare professionals.
ESSENTIALS OF INTELLECTUAL PROPERTY Full of valuable tips, techniques, illustrative real-world examples, exhibits, and best practices, this handy and concise paperback will help you stay up to date on the newest thinking, strategies, developments, and technologies in intellectual property. «Alexander Poltorak and Paul Lerner have written the definitive primer on intellectual property for business professionals. Thorough in its coverage and understandable in its delivery, Essentials of Intellectual Property provides not only an outstanding summary of intellectual property basics, but a useful and sensible strategy for using intellectual property to the best needs of a business. Poltorak and Lerner have combined their in-depth knowledge of patent law with their savvy business skills to yield an indispensable reference for the business professional.» —Jeffrey L. Brandt, Patent Attorney, Former Senior Vice President and Intellectual Property & Licensing Counsel, priceline.com «Alex Poltorak and Paul Lerner have pulled off a mighty feat with Essentials of Intellectual Property. They have crafted a work that is clear for the beginning practitioner while nuanced and sophisticated for the savvy tech transfer and IP management veteran. Lively and often witty writing is a treat not often found in tomes on what can be a dry subject. With Essentials of Intellectual Property, the practitioner has a new literary tool for tying IP strategy to the business reality of tomorrow.» —Edward Kahn, Founder and President, EKMS, Inc., Cambridge, MA «This critically important new volume of work not only provides the professional with a greater knowledge of this vast subject, but also the novice with a better understanding and appreciation for the results of their creative abilities.» —Lawrence J. Udell, Executive Director, California Invention Center, Professor of New Ventures and Entrepreneurship The Wiley Essentials Series—because the business world is always changing…and so should you.